#Low amniotic fluid induction trial#

No differences were found in neonatal morbidity outcomes. No difference was found in perinatal mortality rates, although the study was too underpowered to detect this outcome. The expectant management group had a significantly higher rate of cesarean deliveries resulting from fetal distress, but there was no difference between groups in the rate of cesarean deliveries resulting from dystocia. The expectant management group had a significantly higher rate of cesarean deliveries than the induction group (odds ratio, 1.22 95 percent confidence interval, 1.02 to 1.45 number needed to induce to prevent one excess cesarean delivery, 30). 10 – 12 Expectant management continued until 44 weeks' gestation or until there was an obstetric indication for labor induction. Monitoring consisted of daily kick counts, nonstress tests (NSTs) three times per week ( Table 2), 9 and ultrasound amniotic-fluid–volume assessments two or three times per week ( Table 3). In this study, 3,407 women with pregnancies of at least 41 weeks' gestation were randomized to immediate induction or expectant management with fetal monitoring.

#Low amniotic fluid induction trial#

The Canadian Multicenter Post-term Pregnancy Trial (CMPPT) 8 is the largest individual randomized controlled trial (RCT) to date comparing labor induction at 41 weeks with expectant management.

Elective labor induction before 42 weeks' gestation has been proposed to reduce rates of adverse fetal and maternal complications.